Contrave
CONTRAVE® is a prescription-only, FDA-approved weight-loss medication believed to work on two areas of your brain—the hunger center and the reward system—to reduce hunger and help control cravings. CONTRAVE contains two medicines, bupropion and naltrexone. These well-known drugs have been prescribed separately for years—bupropion for depression and smoking cessation, and naltrexone for alcohol and opioid dependence.
CONTRAVE has a well-studied safety and tolerability profile. Three long-term (56 weeks) studies have shown that patients who add CONTRAVE lose approximately 2 to 4 times more weight than with diet and exercise alone.3 In one study, patients who also participated in an intensive diet and exercise program and remained on CONTRAVE for a full year, lost 25 pounds on average.